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. Author manuscript; available in PMC: 2013 Jun 25.
Published in final edited form as: Cardiovasc Res. 2004 Oct 1;64(1):61–71. doi: 10.1016/j.cardiores.2004.05.011

Fig. 6.

Fig. 6

Tyrosine phosphorylation of STAT1 and STAT3 by ischemic PC in wild-type and IL-6−/− mice. Nuclear extracts were prepared from mice that underwent a sham operation (control), and from the ischemic/reperfused region of preconditioned (PC) wild-type and IL-6−/− mice that were euthanized 30 min after the sixth reperfusion. Upper panels: Western blots showing that the immunoreactivity of tyrosine-phosphorylated STAT1 (panel A) and STAT3 (panel B) in nuclear extracts increased markedly 30 min after ischemic PC in wild-type mice, and that this increase was significantly attenuated in preconditioned IL-6−/− mice. Lower panels: Densitometric analysis of tyrosine-phosphorylated STAT1 and STAT3 in nuclear extracts at 30 min after PC. Data are mean ± S.E.M.