Table 3.
Effects of carbon dots on T lymphocyte subsets in spleen of BALB/c mice
| Groups | CD4+ (%) | CD8+ (%) | CD4+/CD8+ |
|---|---|---|---|
| Saline |
25.97 ± 0.65 |
9.94 ± 1.01 |
2.63 ± 0.21 |
| Carbon dots |
|
|
|
| 2 mg/kg |
24.95 ± 0.20 |
12.54 ± 0.26**↑ |
1.99 ± 0.04**↓ |
| 10 mg/kg |
24.31 ± 0.41**↓ |
11.00 ± 0.14 |
2.21 ± 0.05**↓ |
| 50 mg/kg | 26.51 ± 0.44 | 12.75 ± 0.12**↑ | 2.08 ± 0.04**↓ |
The effects were recorded 1 day after administration. Data are presented as mean ± standard deviations, n = 5. **P < 0.01 compared with the saline group (control). Significant difference was calculated by one-way ANOVA using SPSS19.0.