Table 2.
Genes showing differential expression between salmon louse strains differing in EMB susceptibility
| Accession no. | Annotation |
Experiment 1 |
Experiment 2 |
||
|---|---|---|---|---|---|
| Fold change (PT/S) | p-value | Fold change (PT/S) | p-value | ||
|
Ligand gated ion channel (<1%) |
|
|
|
|
|
|
ADD24187.1 |
Neuronal acetylcholine receptor subunit alpha-3 |
-3.21 |
7.59E-05 |
-2.52 |
4.29E-03 |
|
Metabolism of xenobiotics (<1%) |
|
|
|
|
|
|
ACO15001.1 |
Cytochrome P450 3A24 |
-1.48 |
1.95E-03 |
-1.31 |
4.13E-02 |
|
Regulation of synapse development (<1%) |
|
|
|
|
|
|
ADD24462.1 |
Cerebellin-3 |
-1.86 |
3.60E-04 |
-4.91 |
3.53E-06 |
|
Eye lens proteins (<1%) |
|
|
|
|
|
|
ADD38111.1 |
Beta-crystallin A1 |
2.33 |
6.79E-05 |
1.37 |
1.35E-02 |
|
Transporters (2%) |
|
|
|
|
|
|
NP_001116712.1 |
Solute carrier family 8 (sodium/calcium exchanger) |
-2.10 |
3.63E-04 |
-4.38 |
1.74E-05 |
|
EFX88361.1 |
Alpha subunit of Na+/K+ ATPase |
-1.67 |
2.21E-04 |
-2.08 |
5.34E-05 |
|
ACO12613.1 |
Excitatory amino acid transporter 3 |
-1.42 |
1.10E-04 |
-1.34 |
4.96E-02 |
|
Cytoskeleton proteins (26%) |
|
|
|
|
|
|
ADD38332.1 |
Troponin I |
-1.77 |
4.85E-05 |
-2.61 |
1.17E-06 |
|
XP_001950563.1 |
Muscle LIM protein |
-1.67 |
1.57E-04 |
-2.30 |
1.32E-06 |
|
AAA17371.1 |
Fast myosin heavy chain |
-2.11 |
1.73E-03 |
-6.23 |
1.68E-06 |
|
ACO13186.1 |
Myosin light chain alkali |
-2.65 |
1.69E-05 |
-3.38 |
8.46E-06 |
|
ACO12924.1 |
Myosin light chain alkali |
-2.06 |
1.16E-05 |
-3.69 |
9.66E-06 |
|
ABU41018.1 |
Collagen alpha-1 chain |
-1.38 |
1.51E-03 |
-6.85 |
2.61E-05 |
|
EFV61840.1 |
Smoothelin |
-1.43 |
4.03E-04 |
-1.85 |
6.25E-05 |
|
ACO12887.1 |
Troponin T |
-1.73 |
1.04E-03 |
-2.93 |
8.12E-05 |
|
ADV40202.1 |
Troponin 1 |
-1.94 |
1.87E-03 |
-2.93 |
3.23E-04 |
|
AAW22542.1 |
Myosin light chain |
-1.76 |
1.00E-03 |
-2.23 |
3.73E-04 |
|
ACO10528.1 |
Troponin C, isoform 1 |
-1.91 |
1.69E-03 |
-2.22 |
5.12E-04 |
|
ACO12630.1 |
Troponin C, isoform 1 |
-1.61 |
3.01E-05 |
-1.51 |
5.92E-04 |
|
ACO12421.1 |
Tropomodulin |
-1.51 |
1.17E-04 |
-2.37 |
1.01E-03 |
|
ACO12794.1 |
Troponin C, isoform 1 |
-2.07 |
6.14E-05 |
-1.60 |
2.85E-03 |
|
ACO14751.1 |
Troponin C, isoform 1 |
-2.12 |
4.94E-05 |
-1.56 |
4.18E-03 |
|
ACO11818.1 |
Torso-like protein precursor |
-1.83 |
5.11E-05 |
-1.82 |
9.67E-03 |
|
ACO11077.1 |
Troponin C, isoform 1 |
-1.92 |
6.27E-05 |
-1.48 |
1.56E-02 |
|
Regulation of actin cytoskeleton (<1%) |
|
|
|
|
|
|
XP_002407362.1 |
Paxillin |
-2.79 |
8.32E-07 |
-1.48 |
2.28E-03 |
|
Calcium transport (<1%) |
|
|
|
|
|
|
NP_001032719.1 |
Sarco/endoplasmic reticulum calcium transporting ATPase |
-2.15 |
8.58E-07 |
-2.46 |
2.15E-04 |
|
Calcium binding (1%) |
|
|
|
|
|
|
XP_002734090.1 |
Calmodulin-like |
-1.60 |
6.41E-05 |
-2.46 |
3.25E-04 |
|
ACO11757.1 |
Sarcoplasmic calcium-binding protein, beta chain |
-3.18 |
2.05E-06 |
-3.58 |
1.28E-03 |
|
Cuticle proteins (4%) |
|
|
|
|
|
|
ADD24515.1 |
Cuticle protein 6 |
-2.29 |
1.79E-03 |
-12.28 |
4.75E-04 |
|
ABU41025.1 |
Cuticle protein |
-2.57 |
2.78E-04 |
-12.91 |
1.88E-03 |
|
ACO14885.1 |
Cuticle protein CP14.6 precursor |
-1.77 |
7.50E-04 |
-3.40 |
4.67E-03 |
|
Proteolysis (12%) |
|
|
|
|
|
|
ADD38666.1 |
Matrix metalloproteinase-9 |
-2.29 |
1.07E-05 |
-7.35 |
1.84E-06 |
|
ADD38283.1 |
Kunitz/BPTI-like toxin |
-2.45 |
5.43E-06 |
-1.79 |
2.50E-04 |
|
ABU41053.1 |
Metalloproteinase |
-5.61 |
7.00E-06 |
-4.38 |
3.99E-04 |
|
BAG74353.1 |
Metalloproteinase |
14.83 |
8.20E-05 |
18.61 |
4.64E-04 |
|
ACO11096.1 |
Serine carboxypeptidase CPVL precursor |
1.58 |
2.44E-04 |
1.36 |
1.21E-02 |
|
ABU41117.1 |
Metalloproteinase |
-2.72 |
6.62E-05 |
-1.41 |
1.82E-02 |
|
AAS91793.1 |
Intestinal trypsin 2 precursor |
7.73 |
1.90E-06 |
1.82 |
2.52E-02 |
| AAS91795.1 | Intestinal trypsin 4 precursor | 1.48 | 6.69E-04 | 1.42 | 2.79E-02 |
Annotated genes (57%) were sorted by the significance of differential expression between strains in experiment 1 and arranged by biological function. Features with identical annotation were removed prior to categorising biological function. Also indicated is the percentage representation for each functional category in the total number of annotated genes (129 genes).