Skip to main content
. Author manuscript; available in PMC: 2013 Jun 25.
Published in final edited form as: Adv Drug Deliv Rev. 2010 Sep 29;63(7):539–546. doi: 10.1016/j.addr.2010.09.011

Figure 1.

Figure 1

Different degree of blood-brain barrier penetration of three different radiolabeled drugs revealed by PET measurements in humans (A: [18F]ciprofloxacin; B: racemic [11C]verapamil; C: [11C]ST1859). Shown are transaxial PET summation images depicting radioactivity distribution in brain for the duration of the PET scan after iv administration of the radiolabeled drug. The radiation scale is set from 0 to 0.5 (A) and 0 to 2.0 (B, C) standardized uptake value (SUV). PET images were recorded on an Advance PET scanner (General Electrics Medical Systems). The chemical structures of each drug are shown above the PET images.