Table 2.
Distribution of the c-Met-N375S genotypes in relation to clinicopathological parameters in NSCLC patients. a
| Characteristics | c-Met-N375S genotypes | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Total | A/A | A/G+G/G c | |||||||
| n | N (%) | n | (%) | ||||||
| Overall b 206 | 177 | (85.9) | 29 | (14.1) | |||||
| Clinicopathological parameters | |||||||||
| Age | <70 | 109 | 96 | (88.1) | 13 | (11.9) | |||
| ≧70 | 97 | 81 | (83.5) | 16 | (16.5) | ||||
| Sex | Male | 123 | 105 | (85.4) | 18 | (14.6) | |||
| Female | 83 | 72 | (86.7) | 11 | (13.3) | ||||
| Smoker | Yes | 109 | 93 | (85.3) | 16 | (14.7) | |||
| No | 63 | 54 | (85.7) | 9 | (14.3) | ||||
| Tumor type d | |||||||||
| ADC | 133 | 117 | (88.0) | 16 | (12.0) | ||||
| SCC | 61 | 50 | (82.0) | 11 | (18.0) | ||||
| LCC | 12 | 10 | (83.3) | 2 | (16.7) | ||||
| Tumor stage | |||||||||
| I + II | 88 | 75 | (85.2) | 13 | (14.8) | ||||
| III + IV | 67 | 61 | (91.0) | 6 | (9.0) | ||||
a. The P value was analyzed by Pearson χ2 test and all P values were > 0.05. b. Total number of sample in some categories is less than the overall number analyzed because clinical data were not available for these patients. c. The risk genotype was defined as A/G+G/G genotypes. d. ADC: adenocarcinoma, SCC, squamous cell carcinoma, LCC, large cell carcinoma.