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. Author manuscript; available in PMC: 2014 Jun 10.
Published in final edited form as: Exp Cell Res. 2013 Mar 19;319(10):1431–1442. doi: 10.1016/j.yexcr.2013.02.017

Figure 6. Extracellular Acidification Rate (ECAR) shows an increase in glycolysis during MOSE cell progression.

Figure 6

Extracellular acidification rate (ECAR), an indication of the rate of glycolysis was modified by oligomycin, carbonylcyanide-p-trifluoromethoxyphenyl hydrazone (FCCP), and rotenone (see Fig.5). (A) Image of representative experiment where A is oligomycin treatment, B is FCCP treatment and C is rotenone treatment, measured over 2 h; (B) Change in ECAR over baseline after olygomycin treatment, where So treatment for 3 passages decreased glycolysis rate; (C) Basal ECAR levels in MOSE cells, where MOSE-L and MOSE-L w/ So treatment have an increased rate of glycolysis at basal conditions. Data are presented as mean ± SEM. Different from MOSE-E *p 0.01, **p 0.001.