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. Author manuscript; available in PMC: 2013 Jun 25.
Published in final edited form as: J Mol Med (Berl). 2012 Sep 12;91(3):381–393. doi: 10.1007/s00109-012-0955-3

Fig. 1.

Fig. 1

LOH, copy number loss, and hypermethylation of SH3GL2 in primary NSCLC tumors. a Two sets of primers (UniSTS 12760 and 28906) from the intragenic D9S157 locus of the SH3GL2 gene were examined. LOH occurs when allelic loss was observed at both marker loci (indicated by arrows) in the tumor (T) compared to the corresponding normal (N). b FISH analysis revealed loss of SH3GL2 copy (orange red, arrows) on 9p22 compared to control 9p centromeric probe CEP9 (green). c No significant changes were observed in the methylation pattern of SH3GL2 in the 12 primary NSCLC tumors analyzed compared to corresponding control tissues