Table 3.
Glycaemic control and weight gain in pregnant women receiving ILPS or NPH insulin.
| ILPSg | No. pt | NPHg | No. pt | P | |
|---|---|---|---|---|---|
| FCBG mg/dL (mmol/L) | |||||
| Before enrollment | |||||
| Total | 100.7 ± 15.1 (5.6 ± 0.8) |
21 | 100.6 ± 17.4 (5.6 ± 1.0) |
25 | ns |
| T2DM | 110.0 ± 7.8 (6.1 ± 0.4) |
4 | 109.8 ± 15.8 (6.1 ± 0.9) |
12 | ns |
| GDM | 98.6 ± 15.8 (5.5 ± 0.9) |
17 | 92.2 ± 14.5 (5.1 ± 0.8) |
13 | ns |
| At the end of pregnancy | |||||
| Total | 93.6 ± 13.4** (5.2 ± 0.7) |
30 | 95.7 ± 10.8* (5.3 ± 0.6) |
28 | ns |
| T2DM | 89.2 ± 12.7* (4.9 ± 0.7) |
4 | 95.5 ± 8.2° (5.3 ± 0.4) |
13 | ns |
| GDM | 94.3 ± 13.5* (5.2 ± 0.7) |
26 | 95.8 ± 12.8* (5.3 ± 0.7) |
15 | ns |
| HbA1c% (mmol/L) | |||||
| At the end of pregnancy | |||||
| Total | 5.4 ± 1.1 (36.0 ± 12.2) |
34 | 5.3 ± 0.7 (34.4 ± 8.1) |
33 | ns |
| T2DM | 5.8 ± 1.1 (39.6 ± 12.6) |
7 | 5.4 ± 0.7 (36.8 ± 8.2) |
18 | ns |
| GDM | 5.3 ± 1.1 (35.0 ± 12.1) |
27 | 5.0 ± 0.6 (31.5 ± 7.2) |
15 | ns |
| Weight gain (kg) | |||||
| At the end of pregnancy | |||||
| Total | 10.4 ± 6.1 | 53 | 9.9 ± 4.2 | 36 | ns |
| T2DM | 12.0 ± 6.1 | 7 | 10.8 ± 4.9 | 18 | ns |
| GDM | 10.2 ± 6.1 | 46 | 9.1 ± 3.3 | 18 | ns |
FCBG: fasting capillary blood glucose; T2DM: type 2 diabetes mellitus; GDM: gestational diabetes mellitus.
Paired t-test's P between preenrollment versus the end of pregnancy: *ns; **0.02; °0.004.