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. 2013 Jun 17;9:29. doi: 10.1186/1744-8069-9-29

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Copyright © 2013 Ma et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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LPA₁or LPA₃receptor-mediated calcium mobilization by exogenous LPA species. After the addition of 18:1 (panel a and f), 20:4 (panel b and g), 16:0 (panel c and h), 18:0 (panel d and i) or 14:0 (panel e and j) LPA with defined concentrations (3, 10, 30, 100, 300 nM and 1, 3, 10 μM) into the B103 cells expressing LPA₁ or LPA₃ receptor, calcium mobilization assay was immediately performed. “ED₅₀” and “Max resp” represent the half-maximal effective dose and maximal response, respectively.