Table 1.
Antioxidant effect of salvianolic acid B in vitro.
| Cells/tissues | Effects | Reference |
|---|---|---|
| ECV304 | Activity of SOD, release of NO, aggregation of Ca2+. |
Luo et al., 2002 [18] |
|
| ||
| SCs | Generation of ROS, generation of 8-OHDG, expression of Bax, AIF nuclear translocation, cytochrome C release, caspase of the enzyme 3, 9, cleavage of PARP, expression of Bcl-2. |
Sun et al., 2012 [19] |
|
| ||
| HASMCs | Activity of gelatinolytic, scavenge H2O2. |
Zhang and Wang, 2006 [20] |
|
| ||
| SH-SY5Y | Scavenge O2
+ and OH, reduce oxidative damage. |
Liu et al., 2006 [21] |
Note: HEK293T cell: human embryonic kidney cells; HO-1: heme oxygenase-1; ROS: reactive oxygen species; Nrf2: nuclear factor 2–related factor 2; SOD: superoxide dismutase; MDA: malondialdehyde; ECV304: human umbilical vein endothelial cells; TMP: tetramethylpyrazine; HASMCs: human aortic smooth muscle cells; 8-OHDG: 8-hydroxy-2-deoxyguanosine; SCs: Schwann cells; MMP-2: matrix metalloproteinase-2; PARP: poly ADP-ribose polymerase.