. 2012 Sep 6;72(3):427–436. doi: 10.1136/annrheumdis-2012-201742

Table 3.

Top hit association results

Type of analysis		Stage 1		Stage 2		Stage 1 and 2 (combined)
SNP tested	Adjustments	OR (95% CI)	p Value	OR (95% CI)	p Value	OR (95% CI)	p Value
rs13361160	Age, BMI, and 4 PCs	1.30 (1.19 to 1.42)	1.18×10⁻⁸	1.06 (0.98 to 1.16)	0.16	1.17 (1.10 to 1.24)	4.67×10⁻⁷
(minor allele=C, other allele=T, MAF=43.5%)		1.30 (1.19 to 1.42)	1.18×10⁻⁸	1.06 (0.98 to 1.16)	0.16	1.17 (1.10 to 1.24)	4.67×10⁻⁷
Sensitivity analysis; joint pain only
rs13361160	Age, BMI, and 4 PCs	1.30 (1.19 to 1.42)	1.18×10⁻⁸	1.10 (0.97 to 1.25)	0.15	1.23 (1.14 to 1.32)	3.43×10⁻⁸
(minor allele=C, other allele=T, MAF=43.5%)		1.30 (1.19 to 1.42)	1.18×10⁻⁸	1.10 (0.97 to 1.25)	0.15	1.23 (1.14 to 1.32)	3.43×10⁻⁸

In both analyses the effect estimates of the models refer to the minor allele (=effect allele).

BMI, body mass index; MAF, minor allele frequency.