Table 3.
Relationship between change in plasma lipids and baseline IL-6 tertiles during weight loss1
| Factor | Total Cholesterol | LDL-C | HDL-C | Triglycerides (log10) | Insulin (log10) | Si (log10) | ||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| β(se) | p | β(se) | p | β(se) | p | β(se) | p | β(se) | p | β(se) | p | |
| Age (yrs) | 0.7471 (0.3769) |
0.0489 | 0.5038 (0.3451) |
0.1459 | 0.1504 (0.1242) |
0.2277 | 0.0026 (0.0019) |
0.1699 | −0.0036 (0.0018) |
0.0436 | 0.0092 (0.0026) |
0.0006 |
| IAAT | 0.0772 (0.0634) |
0.2253 | 0.0676 (0.0549) |
0.2201 | −0.0378 (0.0228) |
0.0984 | 0.0011 (0.0004) |
0.0031 | 0.0011 (0.0003) |
0.0034 | −0.0024 (0.0005) |
<0.0001 |
| Baseline | ||||||||||||
| IL6 (pg/mL) |
0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||||||
| ≤1.16 1.17–1.7 |
0.0884 (8.0199) |
0.9153 | 1.0305 (6.9239) |
0.4528 | −3.9776 (2.9889) |
0.4141 | 0.04407 (0.0561) |
0.1292 | 0.0311 (0.0593) |
0.6789 | −0.1850 (0.0902) |
0.0647 |
| >1.7 | 3.0309 (8.0648) |
8.1871 (6.9768) |
−2.0212 (2.9984) |
−0.0723 | 0.0523 (0.0598) |
−0.829 (0.0902) |
||||||
| Race | ||||||||||||
| (White vs.Black) |
5.5457 (4.6050) |
0.2299 | 3.7329 (4.2044) |
0.3757 | −3.9937 (1.5249) |
0.0095 | 0.1444 (0.0230) |
<0.0001 | −0.0456 (0.0221) |
0.0362 | 0.2201 (0.0326) |
<0.0001 |
| Visit | −2.7972 (4.1007) |
0.0511 | −3.5108 (3.4383) |
0.0280 | 4.2739 (1.5831) |
0.0015 | −0.0976 (0.0302) |
<0.0001 | −0.0961 (0.3236) |
<0.0001 | 0.0674 (0.0491) |
<0.0001 |
| Baseline | ||||||||||||
| IL6 (pg/mL) *visit |
0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | ||||||
| ≤ 1.16 1.17–1.7 |
−5.0884 (5.0458) |
0.5689 | −2.1198 (4.1542) |
0.6353 | −0.4114 (2.0151) |
0.6996 | −0.0365 (0.0403) |
0.1321 | 0.0021 (0.0435) |
0.6550 | 0.1051 (0.0662) |
0.1919 |
| >1.7 | −3.8249 (4.9417) |
−3.8658 (4.0595) |
−1.6321 (1.9830) |
0.0475 (0.0400) |
−0.0340 (0.0435) |
0.1032 (0.0655) |
||||||
1
Abbreviations: IAAT, intraabdominal adipose tissue; IL-6, interleukin-6.