Table 2.

Surgical characteristics and perioperative outcomes of the first stage of two-stage hepatectomy

Study	Patients, n	Extrahepatic disease	Preoperative chemotherapy, %	Response ratea, %	Synchronous colorectal resection, %	Liver resection, %	Ablation, %	Operative portal vein ligation/embolization, %	Postoperative morbidity, %	Postoperative mortality, %
Turrini et al.25	48	No	100	NR	37	87	67	0	10	0
Tsim et al.26	38	No	97	NR	0	100	0	0	11	0
Narita et al.27	80	Yes	84	100	40	99	31	4	14	0
Muratore et al.24	47	Yes	79	92	50	100	0	23	19	0
Brouquet et al.23	65	No	100	100	29	100	3	0	25	0
Bowers et al.22	39b	Yes	74	NR	31	100	8	0	23	0
Tsai et al.21	45	Yes	71	NR	50	91	29	73	26	4c
Wicherts et al.20	59	Yes	97	100	20	100	5	56	20	0
Pamecha et al.19	14	No	100	79	NR	100	0	0	0	0
Tanaka et al.18	24	No	64	NR	NR	100	0	71	13	0
Total	459		88	97	35	98	17	20	17
Range			64–100	79–100	0–50	87–100	0–67	4–71	0–26

^aIncludes partial or stable radiological response to chemotherapy.

^bSeries included patients with liver metastases from colorectal cancer (n = 33), neuroendocrine tumours (n = 3), gastrointestinal stromal tumour (n = 1), ocular melanoma (n = 1) and salivary gland carcinoma (n = 1).

^cTwo postoperative deaths: one from liver insufficiency and one from pulmonary embolus.

NR, not reported.