Table 4.

Survival outcomes after completion of two-stage hepatectomy

Study	Median follow-up, months	Median DFS post-TSH, months	3-year DFS post-TSH, %	5-year DFS post-TSH, %	Median OS in non-completion of TSH, months	Median OS post-TSH, months	3-year OS post-TSH, %	5-year OS post-TSH, %
Turrini et al.25	41	NR	24	14	19	44	59	35
Tsim et al.26	19	18a	27a	NR	29	35	50a	NR
Narita et al.27	30	NR	15b	8b	19	40	59	32
Muratore et al.24	24d	8	10	NR	12	38	65	NR
Brouquet et al.23	50	NR	20	20	25	NR	84	64
Bowers et al.22	12	NR	NR	NR	10c	24c	28c	NR
Tsai et al.21	NR	NR	NR	NR	10	36	58	NR
Wicherts et al.20	24	NR	26	13	11	39	60	42
Pamecha et al.19	43	12	NR	NR	NR	33	70	50
Tanaka et al.18	NR	NR	6	NR	NR	NR	33	NR
Median	27		20		16	37	59	42
Range	12–50		6–27		10–29	24–44	28–84	32–64

^aIn patients with R0 liver resection.

^bIn patients who underwent preoperative chemotherapy.

^cSurvival outcomes in patients with CLM only.

^dMean value.

TSH, two-stage hepatectomy; CLM, colorectal liver metastases; NR, not reported; DFS, disease-free survival; OS, overall survival.