Table 1.

Comparison of baseline characteristics between ever-smokers and never-smokers

	Never smokers (n = 451)	Ever smokers (n = 444)
Age* (mean, SD)	49.98 (±10.92)	48.53 (±11.03)
Sex (female)	348 (77.16%)	277 (62.39%)
EDSS† (median, IQR)	5.5 (3.5)	6 (3)
MSSS (mean, SD)	5.13 (±2.70)	5.93 (±2.52)
Disease duration (mean, SD)	17.70 (±10.15)	15.89 (±9.51)
Age at the onset (mean, SD)	32.29 (±9.97)	32.75 (±9.70)
Type of the disease
Relapsing-remitting	226 (50.11%)	217 (48.87%)
Primary-progressive	51 (11.31%)	51 (11.49%)
Secondary-progressive	174 (38.58%)	176 (39.64%)
Disease modifying treatment ≥1 year	173 (38.36%)	183 (41.22%)

*Age at the last clinic visit.

†EDSS recorded at the last clinic visit.