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. 2013 Jun 12;41(Web Server issue):W486–W491. doi: 10.1093/nar/gkt486

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — Comparison of significantly changing positions between two RNAs. Top and bottom halves of the figure demonstrate influenza strains A/Leningrad/134/57 and its cold-adapted temperature-sensitive mutant A/Leningrad/134/47/57, respectively. Each row corresponds to a particular temperature difference. Positions in which base pairing probabilities significantly change with temperature elevation in both sequences and those where these changes only affect one of the sequences are marked blue and orange, respectively. Position numbers are indicated at the top of the alignment.