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. 2013 Jun 8;41(Web Server issue):W232–W237. doi: 10.1093/nar/gkt471

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© The Author(s) 2013. Published by Oxford University Press.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 2. — Projecting the phyletic patterns of two coevolving genes onto the tree. CoPAP allows automatic visualization of the presence–absence pattern for a given pair of genes. The pattern for a given pair is mapped onto the tree with taxa names colored according to presence in both (‘11’, red), absence in both (‘00’, gray), presence in the first only (‘10’, green) or presence in the second only (‘01’, blue). Here, the patterns of COG4521 (ABC-type taurine transport system, periplasmic component) and COG4525 (ABC-type taurine transport system, ATPase component) are presented. In this case, the high similarity in their phyletic patterns (as seen by the dominant red and gray colors) is in line with CoPAP’s inference of a statistically significant coevolution.