TABLE 1.

Immunization regimen and challenge^a

No. of macaques	Group	Prime (wk 0, oral + intranasal; wk 12, intratracheal)	Boost (wk 24, intramuscular; wk 36, intramuscular)
8	I	Ad5hr-SIV env/rev	SIV gp120 in MPL-SE (100 μg)
7	II	Ad5hr-SIV env/rev + Ad5hr-SIV gag	SIV gp120 in MPL-SE (100 μg)
8	III	Ad5hr-SIV env/rev + Ad5hr-SIV nef	SIV gp120 in MPL-SE (100 μg)
8	IV	Ad5hr-SIV env/rev + Ad5hr-SIV gag + Ad5hr-SIV nef	SIV gp120 in MPL-SE (100 μg)
8	V	Ad5hr-SIV env/rev	SIV peptomer in PBS (100 μg)
8	VI	Ad5hr vector	MPL-SE

^aThe intrarectal challenge at week 42 for all immunization groups was SIV_mac251 at a 1:10 dilution in PBS.