Table 6.
Areas Under the Curve for Predicting Progression from Normal Glucose Tolerance to Impaired Glucose Tolerancea
Variable | AUC | 95% CI, lower limit | 95% CI, upper limit | p value versus MQ |
MQ | 0.697 | 0.641 | 0.753 | — |
Fasting insulin | 0.640 | 0.580 | 0.701 | 0.0022 |
Fasting glucose | 0.605 | 0.543 | 0.667 | 0.0031 |
BMI | 0.590 | 0.526 | 0.654 | 0.0009 |
HOMA-IR | 0.648 | 0.587 | 0.709 | 0.007 |
OGIS | 0.703 | 0.646 | 0.761 | 0.36 |
CI, confidence interval.
MQ was calculated using data obtained at the initial OGTT time point. Areas under the curve were calculated as in Table 3 to compare stable NGT (n = 815) with NGT subjects at baseline that were IGT at the three-year follow-up (n = 84). One-sided t-tests were performed to test the hypothesis that the AUC is greater for MQ. The baseline 2 h glucose has an AUC of 0.76. N = 887 for OGIS.