TABLE 3.
Peptides differentially targeted across ethnic groups
| OLP | Protein | Sequence | Overall frequency of recognition | HLAa | Frequency of recognition per ethnicityb
|
P value | |||
|---|---|---|---|---|---|---|---|---|---|
| AA | C | H | WI | ||||||
| 6 | p17 | ASRELERFAVNPGLL | 13.3 | A11 | 6.8 | 26.9 | 20.5 | 0.0 | 0.0068 |
| 17 | p17/p24 | AADTGNSSQVSQNYPIV | 2.7 | A11, A25 | 0.0 | 15.4 | 0.0 | 0.0 | 0.001 |
| 35 | p24 | WMTNNPPIPVGEIYKRWI | 16.0 | B08, B53 | 25.4 | 23.1 | 2.3 | 9.5 | 0.0035 |
| 36 | p24 | PVGEIYKRWIILGLNKIV | 22.0 | B08, B27 | 30.5 | 42.3 | 9.1 | 4.8 | 0.001 |
| 194 | RT | KIEELRQHLLRWGFTTPDK | 13.3 | B44 | 5.1 | 23.1 | 25.0 | 0.0 | 0.0018 |
| 207 | RT | ELAENREILKEPVHGVYY | 11.3 | A2 | 5.1 | 30.8 | 13.6 | 0.0 | 0.0028 |
a
HLA allele most commonly present among individuals with responses to OLP.
b
AA, African-American; C, Caucasian; H, Hispanic; WI, West Indian.