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. 2013 Apr 10;111(1):44–56. doi: 10.1038/hdy.2013.18

Figure 2.

Figure 2

ClustalX v2.1 multiple sequence alignment of all 28 MHC DRB (218 bp) and two MHC DQB (147 bp) alleles detected in NZSL. Dashes indicate nucleotides that are identical to the nucleotides of the first sequence (DRB_3) in this alignment. Shaded in grey are codons predicted to be involved in antigen binding in humans (Brown et al., 1993). MHC DRB codons which have ω>1 with a significant Bayes Empirical Bayes probability, and are therefore likely to be under positive selection, are indicated by *. No evidence of positive selection acting at MHC DQB was detected.