FIG. 5.

Relative replication of WT and serine mutant viruses in macrophages. Human macrophages were infected with WT or mutant viruses with equivalent amounts of p24. The culture supernatants were collected every week, and the virus replication was determined by measuring the RT activity in those supernatants. P values were determined by a two-sided t test comparing RT values for mutants with those from infection with WT virus.