Gross evaluation of the stomachs from various animal groups. Results showed that rats pretreated orally with (C and D) TQNLC(20) at the doses of 30 and 60 mg/kg, respectively and with (B) omeprazole at 20 mg/kg had considerably reduced areas of gastric ulcer formation compared with (A) rats pretreated with only polysorbate 80 (the ulcer control group). (F) effect of NLC(20) (60 mg/kg) on the ethanol-induced ulcers.
Note: Magnification 1.8×.
Abbreviation: TQNLC, thymoquinone-loaded nanostructured lipid carriers.