Figure 1.

Discriminatory accuracy of the models. Discriminatory accuracy for predicting the development of hepatocellular carcinoma within 10 years was assessed by constructing receiver operating characteristic (ROC) curves and calculating the area under the curve (AUC). A) Subcohort without hepatitis C virus (HCV) test. Four models were developed in this subcohort: model 1 was based on health history; model 2 was based on transaminase only; model 3 was based on health history and transaminase; and model 4 was based on health history, transaminase level, alfa-fetoprotein level, and hepatitis B virus (HBV) status. B) Subcohort with HCV test. A fifth model was added to include the HCV status.