The figures show the mean value ± SD (fold) of the measured mRNA in mouse ear tissue of different treatment groups at 60 h, 84 h, and 240 h. A, IL-23. The changes in IL-23 mRNA between groups were statistically insignificant (N = 6). B, IL-17A. The level of IL-17A mRNA in the IMQ-treated group was increased and was inhibited in the CUR-/CLO-treated groups. C, IL-17F. The level of IL-17F mRNA in the IMQ-treated group increased remarkably and was inhibited in the CUR-/CLO-treated groups. D, IL-22. The level of IL-22 mRNA in the IMQ-treated group was increased significantly and was inhibited in the CUR-/CLO -treated groups. CUR, curcumin; CLO, clobetasol.