Figure 8. Effect of mmu-miR-141 inhibitor or mimic on embryo implantation.

The number of embryos in the mimic (P  = 0.0049) and inhibitor (P  = 0.0016) treated uteri horns were significantly lower than that in the untreated uterine horn(A, B). H&E staining was used to show blastocyst attachment to the luminal epithelium at implantation sites on D5 and no obviously changes was observed in inhibitor and mimic treated uteri horns at implanted sites respectivity(C)(×400). N: untreated uterine horn. C: control(empty plasmid). I: treated with mmu-miR-141 inhibitor. M: treated with mmu-miR-141 mimic.