Table 1. Number of animals included.
Rats operated: 31 | tMCAO: 24 | tMCAO rats excluded based on D3 MRI: 8 | Included in analysis* | ||
tMCAO rats included:16 | M2-treated: 8 | with USPIO: 5 | 8 | ||
without USPIO: 3 | |||||
PBS-treated: 8 | with USPIO: 5 | 8 | |||
without USPIO: 3 | |||||
Sham: 7 | Sham rats excluded based on D3 MRI: 0 | Included in analysis* | |||
Sham rats included: 7 | M2-treated: 2 | with USPIO: 2 | 2 | ||
PBS-treated: 5 | with USPIO: 5 | 3 (2 animals excluded because of incomplete data sets) |
Rats that had a complete set of longitudinal MRI data.
tMCAO: transient middle cerebral artery occlusion; PBS: Phosphate buffer saline; USPIO: Ultrasmall superparamagnetic particles of iron oxide.