Figure 3. Lack of PTC124 efficacy with a transiently transfected RLuc PTC-reporter.

(A) Incubation with G418 for 24 hours leads to a dose-dependent increase in enzyme activity of transiently transfected PTC-RLuc. (B) 24-hour incubation with PTC124 at concentrations in excess of its reported effective concentration range of 0.1–0 µM has no effect. All data points represent mean ± standard deviation (n = 5).