Table.

Myogenic Tone (MT), Contraction With PE (10 or 30 μmol/L), and Maximal Dilation to FMD (10 μL/min) of Cerebral Arteries Isolated From C57Bl/6 Male Mice^*

Groups	MT (%)	PE (%)	FMD (%)	N
Control conditions	8 ± 1	40 ± 2	25 ± 3	13
+L-NNA (10 μmol/L)	21 ± 4†	46 ± 5	11 ± 1†	12
+PEG-catalase (50 U/mL)	15 ± 3†	43 ± 3	16 ± 1†	12
+PEG-catalase (100 U/mL)	19 ± 7†	46 ± 3	10 ± 2†	3
+BH4 (1 mmol/L)	16 ± 3†	42 ± 4	28 ± 3	11
+L-arginine (5 μmol/L)	12 ± 8	49 ± 5	24 ± 1	6
+PTIO (100 μmol/L)	8 ± 2	40 ± 4	26 ± 2	8
+ODQ (1 μmol/L)	25 ± 12†	49 ± 4	4 ± 2†	4
+DT-3 (25 nmol/L)	7 ± 2	39 ± 6	11 ± 1†	3
+BH4+PTIO	15 ± 4†	39 ± 7	20 ± 4	5
+BH4+PEG-catalase	18 ± 5†	45 ± 5	26 ± 3	6
+BH4+ODQ	12 ± 5	45 ± 4	7 ± 2†	5
+BH4+L-NNA	17 ± 4†	44 ± 3	11 ± 2†	4
+BH4+PTIO+PEG-catalase	21 ± 9†	47 ± 5	9 ± 2†	5
+Pyruvate (3 mmol/L)	8 ± 2	42 ± 3	15 ± 2†	6
+DETC (1 mmol/L)	15 ± 2†	47 ± 3	15 ± 1†	9
+L-NNA+indomethacin (10 μmol/L)	8 ± 3	36 ± 3	10 ± 3†	5
+PEG-catalase+PTIO	7 ± 2	39 ± 4	14 ± 3†	4
+Triciribine (1 μmol/L)	11 ± 3	45 ± 5	3 ± 1†	4
+Apocynin (10 μmol/L)	12 ± 5	45 ± 4	33 ± 4	4
−Endothelium	12 ± 5	39 ± 9	6 ± 1†	5

Note: Data are expressed as mean±SEM.

^*MT, PE, and FMD are expressed as the percentage of the maximal diameter.

^†P<0.05 compared with control conditions.