Table 2. Alternative PPARα 5′UTR exon/intron junctions conform to the GT-AG splice site rule.
Transcript | Exon (bp) | 5′ Donor Splice Site Consensus5′-gtaagt-3′ | 3′ Acceptor Splice Site Consensus5′-PyPyPyPyPyPyncag-3′ | Exon (bp) |
Adipose P1 | 1A (60) | CCTCAGgtgccc | cgttctatagCCAAGA | 2 (87) |
2 (87) | TCACAGgtaaga | cctcctacagATTGGT | 3 (247) | |
Liver P2 | 1B (318) | GGCGAGgtaact | cgttctatagCCAAGA | 2 (87) |
2 (87) | TCACAGgtaaga | cctcctacagATTGGT | 3 (247) | |
Liver P3 | 2A (145) | CTTCTGgtaggt | cctcctacagATTGGT | 3 (247) |
5′ (donor) and 3′ (acceptor) intron splice site consensus sequences are indicated. The sequences at P1, P2 and P3 transcript exon/intron boundaries are shown. Splice site sequences within introns are shown in lowercase; Exons are shown in capitals, and sizes of exons are given. All transcript exon boundaries conform to the GT-AG splice site rule.