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. 2013 Jun 25;8(6):e66356. doi: 10.1371/journal.pone.0066356

Figure 4. NCTD inhibits expression of Smad2 and Smad3 in HK-2 cells induced by TGF-β1.

Figure 4

(a and b) NCTD inhibited expression of Smad2 and Smad3 mRNA in HK-2 cells induced by TGF-β1. * P<0.05 vs. negative control group (TGF-β1 0 ng/ml) and # P<0.05 vs. positive control (TGF-β1 5 ng/ml + NCTD 0 µg/ml). (c and d) NCTD reduced expression of Smad2/3 and p-Smad2/3 proteins in HK-2 cells induced by TGF-β1. * P<0.05 vs. negative control group (TGF-β1 0 ng/ml) and # P<0.05 vs. positive control group (TGF-β1 5 ng/ml + NCTD 0 µg/ml).