Table 2. Risk factors* for MRSA acquisition.
(No./total) or medians with | Colonized | Not Colonized | Univariate logistic regression | Multivariate logistic regression | ||
interquartile range | (N = 32) | (N = 67) | OR (95% CI) | p-value | OR (95% CI) | p-value |
Gender (male) | 53% (17/32) | 52% (35/67) | 1.04 (0.45–2.41) | 1 | ||
Gestational age (days) | 249 (228–266) | 262 (226–279) | 1.00 (0.98–1.01) | 0.27 | ||
Birth weight (grams) | 2729 (1742–3519) | 2490 (1800–3280) | 1.00 (1.00–1.00) | 0.69 | ||
Hospital of birth (Glostrup) | 56% (18/32) | 54% (36/67) | 1.11 (0.47–2.59) | 0.83 | ||
Caesarean section | 53% (17/32) | 30% (20/67) | 2.66 (1.12–6.35) | 0.03 | 3.74 (1.27–11.0) | 0.016 |
Twins or triplets | 41% (13/32) | 24% (16/67) | 2.18 (0.89–5.37) | 0.10 | 1.48 (0.37–5.87) | 0.6 |
nCPAP treatment | 66% (21/32) | 27% (18/67) | 5.20 (2.10–12.88) | <0.001 | 5.88 (1.67–20.7) | 0.006 |
Transferred from tertiary care centre NICU | 9% (3/32) | 23.9% (16/67) | 0.33 (0.09–1.23) | 0.11 | 0.07 (0.006–1.27) | 0.09 |
Chronic lung disease | 6% (2/32) | 3% (2/67) | 2.17 (0.29–16.12) | 0.59 | ||
Intravascular devices | 59% (19/32) | 45% (30/67) | 1.80 (0.77–4.24) | 0.20 | 0.89 (0.20–3.95) | 0.9 |
Treatment with antibiotics | 44% (14/32) | 30% (20/67) | 1.83 (0.76–4.38) | 0.18 | 1.44 (0.33–6.37) | 0.6 |
Days hospitalized | 12.5 (7.25–34) | 9 (4–27) | 1.01 (0.99–1.03) | 0.19 | 0.99 (0.93–1.05) | 0.8 |
MRSA exposure in days | 12.5 (7.25–34) | 8 (4–17) | 1.03 (1.00–1.05) | 0.04 | 3.11 (0.40–24.6)# | 0.28 |
Data with a p-value of 0.2 or less were tested in the multivariate analysis.
Period of MRSA exposure was logarithmically transformed in the multivariate (Logistic Regression) analysis.