Table 1. Influence of L-serine on physiological parameters in pMCAO rats.
Group (n = 6) | HR (beat/min) | MAP (mmHg) | tcPO2 (mmHg) |
Sham-operated | 348±11 | 97.5±5.1 | 83.1±3.8 |
Vehicle | 367±6 | 102.8±4.0 | 82.5±3.5 |
L-serine | 361±7 | 99.4±4.2 | 85.4±3.2 |
Apamin+ChTx | 357±8 | 98.9±5.7 | 84.3±3.7 |
Apamin+ChTx+L-serine | 359±8 | 104.0±3.2 | 82.9±2.7 |
HR, heart rate; MAP, mean arterial pressure; pMCAO, permanent middle cerebral artery occlusion; tcPO2, transcutaneous partial pressure of O2; and ChTx, charybdotoxin.