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. 2013 Jun 25;8(6):e66920. doi: 10.1371/journal.pone.0066920

Table 3. Haplotype association with chronicity and clearance of HBV infection, with the most common haplotype, CGG, as the reference.

Haplotype HBV carriers (%) Non-HBV infected subjects (%) HBV Clearance subjects (%) OR (95% CI)* p* OR (95% CI) p
CGG 597 (59.7%) 256 (52.2%) 256 (49.6%) 1 1
TAT 147 (14.7%) 106 (21.6%) 108 (20.9%) 0.62 (0.45–0.86) 0.0044 1.64 (1.21–2.24) 0.0013
CAT 80 (8%) 49 (10%) 66 (12.8%) 0.70 (0.45–1.09) 0.116 1.98 (1.35–2.90) 0.00041
CGT 102 (10.2%) 41 (8.4%) 50 (9.7%) 1.15 (0.76–1.74) 0.495 1.07 (0.74–1.56) 0.458
TGG 53 (5.3%) 28 (5.7%) 30 (5.8%) 0.70 (0.42–1.17) 0.177 1.31 (0.80–2.13) 0.213

All logistic regression analyses were adjusted for age and sex.

SNP order of haplotype: rs3077, rs9277378, rs3128917.

*

HBV carriers vs. non-HBV infected subjects.

Clearance subjects vs. HBV carriers.