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. 2013 Jun 25;8(6):e66927. doi: 10.1371/journal.pone.0066927

Figure 2. Quantitative real time RT-PCR of selected gene transcripts in somatotroph adenomas, which supported an interaction between E-cadherin expression levels and SA treatment.

Figure 2

The transcripts of (A) RORC (B) ITGAV (C) CTTNBP2 (D) TIMP1 (E) DOK6 (F) MBNL3 (G) NOX4 (H) VLDLR and (I) KCNIP3 in 65 growth hormone-producing adenomas were selected based on the interaction between E-cadherin and SA (p<0.1, interaction tested with continuous E-cadherin, but presented as tertiles), quantified and distributed according to tertiles of E-cadherin mRNA expression (normalized to GAPDH mRNA levels and expressed as relative mRNA levels). The results are presented as the mean ± SEM and presented relative to tertile 1. P-values represent the interaction between E-cadherin and SA in the univariate analysis.