Table 1.

Association of synovial fluid COMP and early and late scintigraphic uptake in the knee.

			Bivariate association with ln sfCOMP
Knee Bone Scan Phase	Knee Joint Site	Bone Scan ICC (95% CIs)	P value*	P value* (adjusted for late phase bone scan)
Early	Medial Knee	0.724 (0.427, 0.863)	< 0.001	0.026
	Lateral Knee	0.671 (−0.009, 0.76)	0.002	0.047
	Sum Medial and Lateral Knee	0.848 (0.363, 0.759)	< 0.001	0.015
	Patellofemoral Knee	0.664 (0.319, 0.838)	0.074	0.495
	Total Knee (sum medial, lateral and patellofemoral)	0.906 (0.607, 0.826)	< 0.001	0.087
				P value* (adjusted for early phase bone scan)
Late	Medial Knee	0.887 (0.775, 0.946)	0.031	0.067
	Lateral Knee	0.864 (0.661, 0.919)	0.122	0.696
	Sum Medial and Lateral Knee	0.902 (0.790, 0.950)	0.012	0.069
	Patellofemoral Knee	0.647 (0.298, 0.832)	0.681	0.010
	Total Knee (sum medial, lateral and patellofemoral)	0.884 (0.760, 0.943)	0.091	0.507

^*P values adjusted by GLM (generalized linear modelling to control for within subject correlation of knee data)

ICC=intra-class correlation coefficient