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. Author manuscript; available in PMC: 2014 Feb 28.
Published in final edited form as: J Med Chem. 2013 Feb 12;56(4):1573–1582. doi: 10.1021/jm3013882

Figure 2.

Figure 2

Modeled structure of SCCP5773 in complex with CDK4/cyclin D1 (brown carbon atoms) overlayed with the crystal structure of the same Ncap bound to CDK2/cyclin A2 (yellow carbon atoms). A Connolly surface representation of cyclin A is shown along with the putative water molecule contributing bridging hydrogen bonds.