FIG. 1.

Expression of nectin-1 in human vaginal epithelium during menstrual cycle. Frozen sections of vaginal tissues from humans during menses (A) and early proliferative (B), proliferative (C), and secretory (D) phases were stained with monoclonal antibody CK6 specific for nectin-1 (red), and the nuclei were visualized by staining with DAPI (blue). Epithelial layers are indicated by the white arrowheads (luminal edge) and yellow arrowheads (basement membrane). The stratum germinativum (SG) and stratum spinosum (SS) are indicated. The bar indicates 100 μm in this and all subsequent figures. This figure is representative of several similar experiments involving between two and four subjects in each menstrual phase.