Table 1.
Study | Materials | Participants, propranolol:placebo | Sex, % | Age, mean (SD) [range] yr | Study protocol | Outcome measures | |
---|---|---|---|---|---|---|---|
| |||||||
Male | Female | ||||||
Cahill et al.11 | Emotional slide story | 11:8 | 47 | 53 | 27.4 (27.6) | 40 mg 60 min before encoding | % recognition story phase 2 |
van Stegeren et al.40 | Emotional slide story | 14:13 | 31 | 69 | Undergraduates | 40 mg 60 min before encoding | % recognition story phase 2 |
O’Carroll et al.19 | Emotional slide story | 12:12 | 17 | 83 | 21.4 (2.45) | 40 mg 60 min before encoding | % recognition story phase 2 |
Reist et al.27 | Emotional slide story | 5:5 | 100 | 44.45 (8.08) | 40 mg 60–90 min before encoding | % recognition phase 2 | |
Reist et al.27* | Emotional slide story | 5:4 | 100 | 50.53 (8.5) | 40 mg 60–90 min before encoding | % recognition story phase 2 | |
van Stegeren et al.37 | Emotional slide story | 15:15 | 23 | 77 | 22.65 | 40 mg immediately before encoding | % recognition story phase 2 |
Maheu et al.41 experiment 1 | Emotional slide story | 11:13 | 100 | [19–36] | 40 mg 65 min before encoding | % free recall story phase 2 | |
Maheu et al.41 experiment 2 | Emotional slide story | 14:13 | 100 | [20–34] | 80 mg 90 min before encoding | % free recall story phase 2 | |
Strange and Dolan42 | Emotionally valenced words | 12:12 | 50 | 50 | [20–39] | 40 mg 90 min before encoding; memory test 10 h later | % recognition word list |
Grillon et al.43† | Fear conditioning | 15:15 | 46 | 53 | 29 (2.8) | 40 mg 60 min before conditioning | Retention fear conditioning |
van Stegeren et al.38 | Emotionally valenced pictures; crossover design | 28:28 | 50 | 50 | 20.93 (2.38) | 80 mg 90 min before encoding; memory test 2 wk later | % recognition pictures |
Weymar et al.44 | Emotionally valenced pictures | 23:23 | 100 | [19–31] | 80 mg 90 min before encoding | % recognition pictures |
SD = standard deviation.
Posttraumatic stress disorder population; data excluded from statistical analysis.
Data excluded from statistical analysis.