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. 2013 Jul;38(4):222–231. doi: 10.1503/jpn.120111

Table 2.

Characteristics of included reconsolidation studies

Study Materials Participants, propranolol:placebo Sex, % Age, mean (SD) [range] yr Study protocol Outcome measures

Male Female
Miller et al., unpublished* Differential fear conditioning 42:25 50 50 25 (4.2) Day 1: learning
Day 2: propanolol 5 min after reactivation
Day 3: LTM test
Skin conductance response to conditioned stimulus during extinction day 3
de Quervain et al.45 Emotionally valenced word list crossover design 14:14 50 50 23.9 (2.9) Day 1: learning
Day 2: 40 mg 60 min before LTM test, 2nd LTM test 2 wk later
Free recall number of words
Kindt et al.46* Differential fear conditioning 40:20 28 72 20.7 (2.4) Day 1: learning;
Day 2: 40 mg 90 min before memory reactivation
Day 3: LTM test
Fear potentiated startle to conditioned stimulus during extinction day 3
Tollenaar et al.47 Emotionally valenced word list 27:26 100 20.6 (2.1) Wk 1: learning
Wk 2: 80 mg 75 min before memory task
Wk 3: memory task
% recognition nouns week 3
Tollenaar et al.34 Script-driven imagery 27:26 100 20.7 (2.2) Wk 1: script preparation
Wk 2: 80 mg 90 min before memory reactivation
Wk 3: Heart rate and skin conductance response to emotional script
Heart rate and skin conductance response week 3
Soeter et al.48* Differential fear conditioning 40:20 25 75 20.4 (3.8) Day 1: learning
Day 2: 40 mg 90 min before reactivation
Day 3: LTM test
Fear potentiated startle to conditioned stimulus during extinction day 3
Kroes et al.49 Emotionally valenced word list 12:12 58 42 24.4 Day 1: learning
Day 2: 40 mg 90 min before reactivation
Day 3: LTM test
% free recall day 3
Schwabe et al.22 Emotionally valenced pictures 13:13 50 50 [18–30] Day 1: learning
Day 2: 40 mg 90 min before reactivation
Day 3: LTM test
% recognition pictures day 3

SD = standard deviation; LTM = long-term memory.

*

Some participants received propranolol with no memory reactivation; these data are excluded from statistical analysis: 19 in Miller et al. (unpublished), 20 in Kindt et al.46 and 20 in Soeter et al.49