Table 2.
Univariate analysis for response
| Variable |
Size |
Necrosis |
Size and necrosis |
|||||||||
| n | RECIST | P value | WHO | P value | Choi | P value | EASL | P value | Choi | P value | Combined Choi | |
| Total lesions | 65 | |||||||||||
| Enhancement | 1.00 | 1.00 | 0.04 | 0.18 | 0.22 | |||||||
| Hypo/iso | 14 | 2 (14) | 2 (14) | 4 (29) | 0 (0) | 3 (21) | 0 (0) | |||||
| Hyper | 51 | 9 (18) | 10 (20) | 31 (61) | 8 (16) | 22 (43) | 12 (24) | |||||
| Necrosis | 1.00 | 0.67 | 0.32 | 0.34 | 0.01 | |||||||
| > 50% | 10 | 1 (10) | 1 (10) | 7 (70) | 0 (0) | 0 (0) | 0 (0) | |||||
| < 50% | 55 | 10 (18) | 11 (20) | 28 (51) | 8 (15) | 25 (45) | 12 (22) | |||||
| Size A (cm) | 0.35 | 1.00 | 1.00 | 1.00 | 1.00 | |||||||
| < 2 | 10 | 3 (30) | 2 (20) | 5 (50) | 1 (10) | 4 (40) | 1 (10) | |||||
| > 2 | 55 | 8 (15) | 10 (18) | 30 (55) | 7 (13) | 21 (38) | 11 (20) | |||||
| Size B (cm) | 0.04 | 0.002 | 0.31 | 0.47 | 0.07 | |||||||
| > 5 | 25 | 1 (4) | 0 (0) | 11 (44) | 2 (8) | 6 (24) | 1 (4) | |||||
| < 5 | 40 | 10 (25) | 12 (30) | 24 (60) | 6 (15) | 19 (48) | 11 (28) | |||||
| Tumor burden | 1.00 | 0.74 | 0.42 | 1.00 | 0.79 | |||||||
| < 50% | 45 | 8 (18) | 9 (20) | 26 (58) | 6 (13) | 18 (40) | 8 (18) | |||||
| > 50% | 20 | 3 (15) | 3 (15) | 9 (45) | 2 (10) | 7 (35) | 4 (20) | |||||
Numbers in parentheses are percentages of lesions meeting criteria. RECIST: Response Evaluation Criteria in Solid Tumors; WHO: World Health Organization; EASL: European Association for the Study of the Liver.