Table 3.
Changes in haematological values between infected versus arteether drug-treated mice.
| Parameter | Experimental group (N = 6) | |||
|---|---|---|---|---|
| (at the end of the experiment after parasite clearance) | t value | P value | ||
| Infected (INF) | Drug-treated arteether (DT AE) | |||
| HGB (g/dL) | 7.93 ± 0.175 | 11.08 ± 0.770 | 29.53 | <0.0001*** |
| RBC (106/mm3) | 5.90 ± 0.201 | 7.73 ± 0.154 | 17.66 | <0.0001*** |
| PCV (%) | 28.92 ± 1.46 | 31.67 ± 1.86 | 2.84 | <0.05* |
| MCV (fL) | 81.07 ± 2.19 | 86.17 ± 5.49 | 2.11 | >0.05NS |
| MCH (pg) | 27.67 ± 1.17 | 27.6 ± 1.23 | 0.10 | >0.05NS |
| MCHC (g/dL) | 33.17 ± 1.08 | 33.35 ± 0.985 | 0.30 | >0.05NS |
| PLT (103/mm3) | 516.7 ± 23.4 | 650 ± 22.8 | 10.00 | <0.0001*** |
| WBC (cells/mm3) | 6957 ± 102 | 8983 ± 475 | 10.22 | <0.001*** |
| Neutrophils (%) | 28.3 ± 0.724 | 37.01 ± 0.708 | 21.08 | <0.0001*** |
| Lymphocytes (%) | 69.70 ± 2.00 | 60.67 ± 1.63 | 8.57 | <0.0001*** |
| Monocytes (%) | 1.0 ± 0.117 | 1.0 ± 0.210 | 8.57 | >0.05NS |
| Eosinophils (%) | 1.0 ± 0.669 | 2.0 ± 0.729 | 8.57 | <0.05* |
The values are given as mean ± SD are statistically significant at t > 2.306, P < 0.05*, P < 0.001**, and P < 0.0001***; not significant at P > 0.05; HGB: hemoglobin; RBC: red blood cells; PCV: packed cell volume; MCV: mean cell volume; MCH: mean cell hemoglobin; MCHC: mean cell hemoglobin concentration; PLT: platelets; WBC: white blood cells.