Figure 1.

A: Evident expansion of endoplasmic reticulum, loss of ribosome, swelling of mitochondria, shortening and reduction in mitochondrial cristae, and vacuolized mitochondria; B: In the matrix, the capillaries were closed and presented with stenosis, no blood cells were found in the capillaries, the tight junction between endothelial cells was evident, and a large amount of collagens surrounded the blood vessels; C: The endoplasmic reticulum in the fibroblasts expanded and a large amount of collages surrounded these fibroblasts.