Table 1. Characteristics of the RUPP, RUPP-PI and combined RUPP risperidone Autism samples.
| RUPP (n=71) | RUPP-PI (n=110) | Combined (n=181) | P-value | |
|---|---|---|---|---|
| Gender (n (%) male) | 56 (78.9%) | 92 (83.6%) | 148 (81.8%) | χ2=0.66, P=0.4177 |
| Baseline age (months) | 106.66±34.5 | 89.96±29.0 | 96.5±32.3 | T=3.51, P=0.0006 |
| Baseline BMI | 18.2±4.9 | 17.7±3.1 | 17.9±3.92 | T=0.85, P=0.40 |
| Ethnicity (n (%)) | χ2=14.9, P=0.02 | |||
| White, non-Hispanic | 51 (71.8%) | 74 (67.3%) | 125 (69.0%) | |
| Black, non-Hispanic | 6 (8.5%) | 20 (18.2%) | 26 (14.4%) | |
| Native American | 0 | 2 (1.8%) | 2 (1.1%) | |
| Asian or Pacific Islander | 7 (9.9%) | 5 (5.5%) | 13 (7.2%) | |
| Hispanic | 2 (2.8%) | 7 (6.4%) | 9 (5.0%) | |
| Black, Hispanic | 0 | 1 (0.9%) | 1 (0.6%) | |
| Other | 5 (7.0%) | 0 | 5 (2.8%) | |
| Duration of treatment | ||||
| Median (range) weeks | 8 (6–8) | 8 (1–8) | 8 (1–8) | χ2=4.08, P=0.54 |
| Final dose (mg) | 1.84±0.63 | 2.09±0.59 | 2.00±0.62 | T=−2.66, P=0.0084 |
| Mean weight gain (kg) | 2.84±2.05 | 2.57±1.51 | 2.68±1.74 | T=0.97, P=0.3317 |
Abbreviations: BMI, body mass index; RUPP, Research Units on Pediatric Psychopharmacology; RUPP-PI, RUPP-psychosocial intervention.