Figure 3.

(A) Varying screen detection capability in relation to tumour growth rate (copied from Esserman et al, 2009). (B) Hypothetical cumulative incidence of breast cancer without (left) or with (right) overdiagnosis based on screening women between 50–68 years (copied from Biesheuvel et al, 2007; red line shows screened women and blue line unscreened women). (C) Meta-analysis of estimates of overdiagnosis: (a) excess cancers as a proportion of cancers diagnosed over whole follow-up period in women invited for screening, (b): excess cancers as a proportion of cancers diagnosed during screening period in women invited for screening. (D) Consequences of overdiagnosis.