Table 2.
IL-6 and IL-4 Expression in Different Brain Regions of SFvF1 and FvSF1 Offspring at Pnd21 (pg/mg protein)
| Brain sections | Treatment | IL-6 | IL-4 | ||||||
|---|---|---|---|---|---|---|---|---|---|
| SFvF1 | FvSF1 | SFvF1 | FvSF1 | ||||||
| Males | Females | Males | Females | Males | Females | Males | Females | ||
| SN | H2O | 48.6±7.6 | 57.4±8.6 | 7.3±1.2 | 6.5±1.5 | 1.6±1.3 | 1.9±1.8 | 4.8±1.0 | 4.8±0.9 |
| HgCl2 | 98.7±30.3 | 79.1±11.4 | 8.3±1.5 | 6.8±0.8 | 0.8±0.8 | 6.0±6.0 | 4.6±0.7 | 5.5±0.5 | |
| HT | H2O | 33.5±8.8 | 36.0±8.6 | 3.9±0.7 | 3.8±0.6 | 4.5±0.5 | 3.6±2.3 | 4.2±0.6 | 3.6±0.4 |
| HgCl2 | 21.8±3.6 | 74.4±23.1 | 4.1±0.3 | 2.8±0.4 | 5.6±4.8 | 4.8±2.8 | 4.2±0.8 | 4.3±0.4 | |
| FCX | H2O | 12.0±5.2 | 6.2±4.9 | 0.6±0.2 | 0.6±0.4 | 1.1±0.4 | 0.8±0.1 | 2.1±0.3 | 2.4±0.3 |
| HgCl2 | 6.2±0.4 | 8.2±3.1 | 0.5±0.1 | 0.5±0.1 | 0.7±0.5 | 2.5±0.9 | 2.7±0.6 | 2.9±0.5 | |
| STR | H2O | 3.0±1.2 | 5.1±0.5a | 2.7±1.3 | 1.2±0.5 | 1.2±0.4 | 0.7±0.1 | 1.8±0.7 | 1.7±0.2 |
| HgCl2 | 3.2±0.1 | 7.6±0.9a | 1.8±0.7 | 1.0±0.3 | 0.5±0.3 | 1.2±0.9 | 2.5±0.4 | 2.4±0.4 | |
| CX | H2O | 2.0±0.7 | 7.9±4.2 | 1.0±0.3 | 0.8±0.3 | 1.2±0.3 | 1.0±0.3 | 1.7±0.6 | 1.6±0.3 |
| HgCl2 | 3.0±0.2 | 7.9±3.0 | 0.7±0.3 | 0.7±0.5 | 1.5±0.4 | 2.3±0.7 | 2.0±0.3 | 2.3±0.3 | |
| HC | H2O | 2.2±0.9b | 4.0±0.9a,b | 0.7±0.4b | 0.8±0.3b | 1.2±0.3 | 0.9±0.2 | 2.0±0.8 | 2.3±0.3 |
| HgCl2 | 1.6±0.1b | 4.6±0.3a,b | 1.4±0.7b | 0.9±0.7b | 0.5±0.3 | 2.4±0.7 | 2.1±0.3 | 2.3±0.2 | |
| CB | H2O | 3.6±1.2 | 4.0±1.4 | 0.8±0.4 | 1.1±0.3 | 1.3±0.2c | 0.9±0.2 | 2.1±0.3 | 2.0±0.3 |
| HgCl2 | 10.9±5.0 | 5.3±0.9 | 2.3±1.5 | 1.6±0.3 | 0.8±0.2c | 2.7±0.9 | 2.1±0.3 | 2.3±0.2 | |
Notes. All results are reported as mean ± SEM. For IL-6, three-way ANOVA indicated significant strain differences for all regions with p < 0.001–0.006; aindicates sex difference of SFvF1 (STR: t = 2.75, p = 0.012; HC: t = 3.16, p = 0.004) and females of each strain (STR: t = 4.73, p = 0.001; HC: t = 5.12, p = 0.001); bindicates strain difference (HC for H2O, t = 3.53, p = 0.002; HgCl2, t = 2.78, p = 0.01). For IL-4, three-way ANOVA indicated significant strain differences for FCX, STR, HC, and CB (p = 0.003–0.024); cindicates that males of each strain differ (t = 2.48, p = 0.018).