The relationship between levels of selected cytokines and chemokines, shedding of vaccine virus, and clinical symptoms for 3 representative children from groups 1, 2, and 3. Viral titers are indicated in black. Levels of 11 cytokines and chemokines are indicated in red, purple, yellow, and green, as shown in the key. Blue arrowheads indicate days of rhinorrhea for the subject in group 1, purple arrowheads indicate days of nasal congestion for the subject in group 2, and green arrowheads indicate days of nasal congestion for the subject in group 2. Abbreviations: IFN, interferon; IL, interleukin; TNF-α, tumor necrosis factor α.