. 2013 Jan 16;207(9):1389–1396. doi: 10.1093/infdis/jit030

Table 2.

Geometric Mean Ratios (GMRs) of Paired Data From Study Interventions

Variable	Intervention Comparison, GMR (95% CI)
	N-9 vs Normosol-R	N-9 vs CS + BX	CS + BX vs Normosol-R
Plasma ^99mTc AUC	8.3 (4.7–15.6)^a	5.7 (3.4–9.4)^a	1.5 (.7–3.3)
Plasma ^99mTc C_max	12.0 (6.8–21.0)^a	8.4 (5.2–13.5)^a	1.4 (.7–3.1)
Plasma ^99mTc T_max	0.21 (.15–.28)^a	0.40 (.25–.66)^a	0.52 (.29–.94)^a
Urine ^99mTc level, h after intervention receipt
0–2	12.2 (6.3–23.6)^a	5.0 (3.1–8.2)^a	2.4 (1.0– 5.8)^a
2–4	5.0 (2.1–11.8)^a	4.0 (1.4–11.4)^a	1.3 (.5–3.8)
4–8	3.6 (1.1–11.4)^a	1.6 (.7–3.4)	2.3 (.5–9.6)
8–12	2.8 (.7–10.6)	1.7 (.7–4.1)	1.7 (.4–7.8)
12–24	1.9 (.8–4.7)	1.7 (.6–4.8)	1.2 (.4–4.3)

Abbreviations: AUC, area under the curve; CI, confidence interval; C_max, maximum concentration; CS + BX, Normosol-R plus coital simulation and endoscopic biopsy; N-9, nonoxynol-9; T_max, time to maximum concentration; ^99mTc, ^99mtechnetium.

^a P < .05, using the t test for pairwise comparison.