Table 1. Mean Variables According to the Weight Z-Score in the Two Groups.
| Weight Z score ≤0, N=52 | Weight Z score >0, N=30 | P Value | |
|---|---|---|---|
| Age, mo | 46.9 ± 35.7 | 50.2 ± 36.8 | 0.5 |
| Sex, male, % | 75.7 | 78.9 | 0.5 |
| Activity index, % | 26.6 ± 15.1 | 20.7 ± 12.6 | 0.005 |
| SCD activity (palmitoleic /palmitic) | 0.14 ± 0.04 | 0.16 ± 0.04 | 0.007 |
| Arachidonic/linoleic index | 0.011 ± 0.008 | 0.015 ± 0.009 | 0.02 |
| Adipocyte volume, pL a | 200.1 ± 70.8 | 324.7 ± 102.6 | < 0.001 |
| Nº preadipocytes per gram of tissue x 105 a | 32.5 ± 26.9 | 29.5 ± 24.3 | 0.8 |
| Adiponectin expression a | 0.56 ± 0.15 | 0.54 ± 0.15 | 0.2 |
| CB1R a | 0.55 ± 0.26 | 0.61 ± 0.29 | 0.9 |
| Insulin receptor a | 0.51 ± 0.21 | 0.52 ± 0.18 | 0.4 |
| IRS1 a | 0.48 ± 0.26 | 0.57 ± 0.21 | 0.7 |
| PPARγ a | 0.84 ± 0.27 | 0.66 ± 0.23 | 0.2 |
| SCD1 a | 0.46 ± 0.30 | 0.50 ± 0.23 | 0.5 |
| SREBP-1c a | 0.54 ± 0.33 | 0.96 ± 0.43 | 0.7 |
| Osteocalcin a | 0.66 ± 0.35 | 0.70 ± 0.38 | 0.5 |
aData are expressed as median and semi-interquartile ranges, p = significance level of Mann-Whitney test.
Abbreviations: CB1R, cannabinoid 1 receptor; IRS1, insulin receptor substrate 1; PPAR, peroxisome proliferator activated receptor gamma; SCD1,stearoyl-CoA desaturase 1; SREBP-1c,stearoyl responsive element binding protein