Skip to main content
. Author manuscript; available in PMC: 2013 Jun 26.
Published in final edited form as: Drug Metab Dispos. 2008 May 12;36(8):1716–1721. doi: 10.1124/dmd.108.020867

Fig. 2.

Fig. 2

Dose response of induction of Nqo1 and Cyp2b10 to OPZ treatment. Total RNA was isolated from adult male C57BL/6 mice after treatment of OPZ (50, 100, 150, 200, 250 mg/kg, i.p., once daily, 4 days). The mRNA levels of Cyp2b10 and Nqo1 were determined by the bDNA signal amplification assay. The data are presented as mean -fold induction ± S.E.M. (n = 5–6); *, significantly different from vehicle (p ≤ 0.05).